Abraxane - Abraxis (Paclitaxel)

Abraxane by Biocon comes in 100 mg inj. form.

• you are allergic to any ingredient in Abraxane
• you have extremely low white blood cell counts (eg, extremely low neutrophil counts)
• you have shingles or chickenpox
• Contact your doctor or health care provider right away if any of these apply to you.

• if you are pregnant, plan to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances (including albumin)
• if you have a bacterial or viral infection, HIV infection, liver or kidney problems, a history of heart problems or heart attack, bone marrow problems, or blood problems (low platelet or neutrophil counts)
• if you are undergoing radiation therapy
• if you have ever had an allergic reaction to an insect sting

Some MEDICINES MAY INTERACT with Abraxane . Tell your health care provider if you are taking any other medicines, especially any of the following:

• Ketoconazole because side effects of Abraxane may be increased
• Warfarin or doxorubicin because side effects may be increased by Abraxane

This may not be a complete list of all interactions that may occur. Ask your health care provider if Abraxane may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

• Abraxane comes with an additional patient leaflet. Read it carefully and reread it each time you get Abraxane refilled.
• Abraxane is usually administered as an injection at your doctor's office, hospital, or clinic. Ask your doctor or pharmacist any questions that you may have about Abraxane .
• If nausea, vomiting, diarrhea, or loss of appetite occurs, do not discontinue your medicine. Ask your doctor or pharmacist for ways to lessen these effects.
• Wear gloves while handling Abraxane .
• If you get Abraxane on your skin, rinse the area thoroughly with soap and water. If you get Abraxane in your eyes, nose, or mouth, flush the area thoroughly with water.
• If you miss a dose of Abraxane , contact your doctor immediately.

Ask your health care provider any questions you may have about how to use Abraxane .

• Some patients develop redness or sores in the mouth or on the lips. These symptoms may occur a few days after treatment with Abraxane and usually decrease or disappear in 1 week. Talk with your doctor about proper mouth care and other ways to prevent or reduce this side effect.
• Abraxane may cause dizziness or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Abraxane . Using Abraxane alone, with certain other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.
• Abraxane contains albumin, which comes from human blood. There is an extremely rare risk of developing a viral disease, or a central nervous system disease called Creutzfeldt-Jakob disease. No cases of viral disease or Creutzfeldt-Jakob disease from albumin have been identified.
• Abraxane may lower your body's ability to fight infection. Prevent infection by avoiding contact with people with colds or other infections. Notify your doctor of any signs of infection, including fever, sore throat, rashes, or chills. Also, do not touch your eyes or the inside of your nose unless you have thoroughly washed your hands first.
• Abraxane may reduce the number of blood cells that are needed for clotting. Report any unusual bleeding, bruising, blood in the stools, or dark, tarry stools immediately to your doctor.
• If you have not had chickenpox or measles, avoid contact with anyone who has either of these diseases or shingles.
• Check with your doctor before having immunizations (vaccinations).
• Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Abraxane .
• LAB TESTS, including blood counts and liver function tests, will be required to monitor your progress and check for side effects. Be sure to keep all doctor and lab appointments.
• Use an effective form of birth control (eg, condoms) during sexual intercourse with a woman of childbearing age while you are using Abraxane .
• Women of childbearing age should use an effective form of birth control (eg, condoms) while using Abraxane .
• PREGNANCY AND BREAST-FEEDING: Abraxane has been shown to cause harm to the human fetus. If you plan on becoming pregnant, discuss with your doctor the benefits and risks of using Abraxane during pregnancy. It is unknown if Abraxane is excreted in breast milk. Do not breast-feed while using Abraxane .

• If you have any questions about Abraxane , please talk with your doctor, pharmacist, or other health care provider.
• Abraxane is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.